Join us in making a difference for people with C9 and other neurodegenerative diseases.

Scientist

Sunnyvale, CA

Corsalex is a Sunnyvale-based biotechnology company developing therapies to treat C9orf72 ALS/FTD. Corsalex is broadly interested in understanding the pathophysiology of this disease and advancing therapeutics to treat it. We are recruiting a scientist to manage our wet lab and conduct early-stage research. Specifically, the scientist will focus on the identification and validation of novel drug targets as well as advancing drugs from hit identification to development stage.

 We are looking for a neurobiologist with deep expertise in cellular models and assay development. The individual should be able to optimize various biophysical, biochemical, molecular, and cellular assays as well as conduct proof-of-concept studies in relevant models. The ideal candidate will be a detail-oriented individual who is self-motivated, independent, possesses a proactive attitude, and has a strong desire to discover novel biology and advance new drugs to treat neurodegenerative diseases.

Qualifications

Required Experience and Expertise:

  • PhD in Neurobiology with a strong research background in molecular and cellular biology

  • Experience in developing and implementing cellular assays

  • Skilled in light and fluorescence microscopy

  • Skilled in molecular biology

  • Able to work independently

  • Able to trouble shoot experiments

  • Critical thinking and passion for scientific discovery

  • Exceptional attention to detail and time management skills

  • Ability to collaborate with others on cross functional teams in a fast-paced, matrixed, environment consisting of internal and external team members

  • Effective verbal and written communication skills

  • Able to adapt to changing priorities and deadlines

  • Physical requirements:

  • Office/Laboratory based position in Sunnyvale, CA

 Preferred Qualifications:

  • Experience in neurodegenerative diseases

  • Experience in 3D cultures

  • Experience in electrophysiology

  • Experience with iPSC cultures and differentiation

  • Postdoctoral experience

Responsibilities

Lab:

  • Testing compounds in an array of cell lines, emphasis on mechanism of action

  • RNAseq and proteomics studies

  • Developing target engagement assays to run in the lab

  • Developing assays as needed

  • Generating data reports and presentations

Management:

  • Responsible for starting up the lab and all associated functions and needs

  • Evaluate new targets

  • Evaluate potential scientific collaborations

  • CROs interaction -evaluate current and new CROs (protocols, cost)

  • CDD management

  • Presents findings internally and contributes to company publications

  • Contributes to the development of patent applications as needed

Benefits

  • The base salary offered will be contingent on candidate’s background and experience

  • Equity

  • All eligible employees may also enroll in medical, dental, and retirement savings plans

 

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment visa at this time.

To apply for this role please email a resume and cover letter to jobs@corsalex.com